Table 1 Demographic, clinical and genetic data in patients with schizophrenia and healthy controls.

From: MTHFR Ala222Val polymorphism and clinical characteristics confer susceptibility to suicide attempt in chronic patients with schizophrenia

Variable

SCZ (n = 957)

HC (n = 576)

F or χ2 (p)

Gender(male/female), n

783/174

263/313

216.8 (<0.001)

Age (years)

47.8 ± 10.2

45.8 ± 12.8

11.7 (<0.01)

Education (years)

9.3 ± 6.4

8.7 ± 3.2

1.5 (0.09)

Smokers/Non-smokers, n

627/318

218/358

117.7 (<0.000)

BMI (kg/m2)

24.5 ± 3.9

25.1 ± 3.9

2.7 (<0.01)

Drinkers/Non-drinkers, n

137/727

121/455

6.2 (0.013)

MTHFR genotype distribution

  

2.0 (0.36)

CC n(%)

298 (38.9)

145 (34.8)

 

CT n(%)

344 (45.0)

202 (48.4)

 

TT n(%)

123 (16.1)

70 (16.8)

 

MTHFR allele frequency

C/T, n

590/940

342/492

0.08 (0.83)

  1. Note: Data is given as mean ± standard deviation; BMI = body mass index; SCZ = schizophrenia; HC = healthy control; MTHFR = Methylenetetrahydrofolate reductase.
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