Table 3 Multiple logistic regression analysis of the MTHFR Ala222Val polymorphism and suicide susceptibility.

From: MTHFR Ala222Val polymorphism and clinical characteristics confer susceptibility to suicide attempt in chronic patients with schizophrenia

Genotype

Attempers n = 125

Nonattempters n = 642

p-valuea

Crude OR (95% CI)

Adjusted OR (95% CI)

p-valueb

MTHFR Ala222Val (HWE = 0.791)

Val/Val

26

99

 

1

1

 

Ala/Val

45

299

0.039

0.61 (0.35–1.01)

0.36 (0.23–0.59)

0.0000

Ala/Ala

54

244

0.52

1.10 (0.64–1.87)

0.97 (0.73–1.28)

0.83

  1. Notes: aChi-squared tests were used to determine differences in genotype distributions between attempters and nonattempters.
  2. bAdjusted for age, gender, smoking, BMI, drinking and marital status.
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