Table 4 Demographic and clinical data in patients with schizophrenia divided with regard to suicide attempt and MTHFR Ala222Val genotypes.

From: MTHFR Ala222Val polymorphism and clinical characteristics confer susceptibility to suicide attempt in chronic patients with schizophrenia

Variable

Attempter

Nonattempter

Ala/Ala

Ala/Val

Val/Val

Ala/Ala

Ala/Val

Val/Val

Gender (male/female),n

32/6

59/5

17/5

212/48

240/40

82/19

Age (year)

45.6 ± 9.7

45.6 ± 9.7

47.1 ± 10.1

49.0 ± 9.4

48.1 ± 9.3

47.9 ± 9.6

Education (year)

9.3 ± 2.3

7.9 ± 2.5

8.6 ± 2.6*

9.3 ± 2.5

9.3 ± 5.8

8.5 ± 2.5

Drinkers/Nondrinkers, n

3/18

20/23

11/39*

13/76

31/243

34/189

Cigarette/day

27.4 ± 5.6

23.9 ± 4.5

21.3 ± 3.8*

22.5 ± 4.8

19.5 ± 10.3

18.8 ± 2.0

Smokers/Non-smokers, n

17/7

32/13

36/18

62/37

180/118

167/76

BMI (kg/m2)

24.9 ± 3.9

25.4 ± 4.3

23.6 ± 3.7

24.7 ± 4.1

24.6 ± 3.9

24.6 ± 3.9

Age of onset (year)

25.0 ± 9.3

23.1 ± 4.8

23.8 ± 6.3

23.4 ± 6.0

23.5 ± 5.4

23.2 ± 4.8

Duration of illness (year)

20.0 ± 8.9

22.3 ± 8.7

23.4 ± 9.6

25.6 ± 9.2

24.6 ± 9.8

24.6 ± 9.1

Antipsychotic dose (CPZ)

459.5 ± 464.0

402.9 ± 175.4

509.7 ± 403.2

446.9 ± 311.9

478.0 ± 448.7

421.3 ± 270.1

PANSS factors (score)

Positive

8.7 ± 4.8

8.8 ± 4.1

8.9 ± 5.1

7.9 ± 4.9

7.4 ± 4.9

7.0 ± 4.3

Negative

19.6 ± 5.2

18.8 ± 6.5

20.9 ± 6.3

3.6 ± 1.2

3.5 ± 1.2

3.6 ± 1.2

Cognitive

7.7 ± 3.0

7.5 ± 2.6

8.4 ± 3.1

8.2 ± 3.5

7.9 ± 3.6

8.1 ± 3.4

Depression

5.0 ± 2.6

4.3 ± 1.9

4.7 ± 2.3

3.6 ± 1.2

3.5 ± 1.2

3.6 ± 1.2

Excitement

4.6 ± 0.9

5.1 ± 2.7

5.2 ± 2.5

4.7 ± 2.0

4.6 ± 1.8

4.6 ± 1.5

  1. Note: Data is given as mean ± standard deviation; BMI = body mass index; PANSS = Positive and negative syndrome scale; CPZ = Chlorpromazine equivalent dose; MTHFR = Methylenetetrahydrofolate reductase.
  2. *p < 0.05.
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