Figure 3 | Scientific Reports

Figure 3

From: Kidney transplant monitoring by urinary flow cytometry: Biomarker combination of T cells, renal tubular epithelial cells, and podocalyxin-positive cells detects rejection

Figure 3

Urinary cell populations in patients with graft deterioration and renal biopsy. (A) Urinary T cells, monocytes/macrophages, PDX-positive cells and TEC in a patient with suspected graft rejection analyzed by flow cytometry. The dot plots show a representative gating strategy. (B) Patients were allocated to the No RX, TCMR or ABMR group according to the histological diagnosis and a control group of stable kidney transplant patients was analyzed. Planet plots illustrating proportions of urinary cell populations in the analyzed groups. Planet rings are proportional to the standard deviation. (C) Subdivision of events (Mean) measured by flow cytometry. SSC – side scatter; FSC – forward scatter; PDX, podocalyxin; EPCAM, epithelial cell adhesion molecule; TEC, tubular epithelial cells; No RX, no rejection; TCMR, T cell-mediated rejection; ABMR, antibody-mediated rejection.

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