Figure 2

(A) The trend of incidence of second primary esophageal cancer by year; (B) The trend of second primary esophageal cancers, stratified by head and neck cancer location; (C) The trend of incidence of synchronous esophageal cancer by year; (D) The trend of synchronous esophageal cancer, stratified by head and neck cancer location; (E) The cumulative incidence of metachronous esophageal cancer in patients with negative index endoscopic screening finding; (F) The cumulative incidence of metachronous esophageal cancer, stratified by head and neck cancer location.