Table 2 Kaplan-Meier estimates of survival probability according to main clinical-pathological variables for the 591 patients under study.

Age

<0.001

0.011

≤67.5 years

296

79.7%

83.2%

>67.5 years

295

67.7%

75.2%

Gender

0.019

0.112

Male

349

71%

77.7%

Female

242

76.8%

81.6%

Tumor location

0.917

0.777

Colon

444

73.7%

79.6%

Rectum

38

72.7%

78.3%

Intent of surgery

<0.001

<0.001

R0 resection

504

79.6%

85.9%

R1-2/No resection

87

38%

39.7%

Depth of invasion (pT)

<0.001

<0.001

pTis

62

91.4%

100%

pT1

91

85.1%

89.6%

pT2

69

84%

89.6%

pT3

227

75.8%

76.2%

pT4

137

51.5%

57.6%

Nodal involvement (pN)

<0.001

<0.001

pN0

350

86.1%

92.4%

pN1

152

63.9%

68.1%

pN2

84

40.2%

47.8%

Systemic metastasis (M)

<0.001

<0.001

M0

472

81.3%

87.9%

M1a

84

46.6%

48.5%

M1b

30

—

—

TNM stage

<0.001

<0.001

Stage 0-I

175

92.6%

97.4%

Stage II

155

80.8%

89.8%

Stage III

142

68.5%

73.8%

Stage IV

114

42.1%

43.8%

Histological type

0.066

0.218

Adenocarcinoma

495

74.6%

80%

Mucinous

82

70.3%

77.2%

Others

14

42.9%

69.6%

Tumor grading

<0.001

<0.001

G1-G2

533

76.1%

81.7%

G3

58

41.7%

49.5%