Table 3 Pathways enrichment analysis of the genes in subtype-specific regulatory networks by WebGestalt (FDR < 0.05).

NSE

hsa04550

Signaling pathways regulating pluripotency of stem cells

1.11E-06

0.0002

10

hsa05166

HTLV-I infection

1.12E-06

0.0002

13

hsa04310

Wnt signaling pathway

7.54E-05

0.0070

8

hsa04950

Maturity onset diabetes of the young

0.0001

0.0070

4

hsa05200

Pathways in cancer

0.0001

0.0070

13

hsa05205

Proteoglycans in cancer

0.0002

0.0086

9

hsa04380

Osteoclast differentiation

0.0003

0.0130

7

hsa05210

Colorectal cancer

0.0003

0.0130

5

hsa04020

Calcium signaling pathway

0.0004

0.0134

8

hsa05224

Breast cancer

0.0006

0.0170

7

hsa04510

Focal adhesion

0.0008

0.0227

8

hsa04022

cGMP-PKG signaling pathway

0.0013

0.0324

7

hsa05213

Endometrial cancer

0.0017

0.0357

4

hsa04360

Axon guidance

0.0017

0.0357

7

hsa05215

Prostate cancer

0.0018

0.0357

5

hsa04974

Protein digestion and absorption

0.0019

0.0357

5

hsa05217

Basal cell carcinoma

0.0021

0.0366

4

hsa04916

Melanogenesis

0.0031

0.0498

5

hsa04933

AGE-RAGE signaling pathway in diabetic complications

0.0031

0.0498

5

SE

hsa04658

Th1 and Th2 cell differentiation

1.68E-06

0.0005

8

hsa05166

HTLV-I infection

3.16E-06

0.0005

12

hsa05200

Pathways in cancer

1.10E-05

0.0011

14

hsa05321

Inflammatory bowel disease (IBD)

2.60E-05

0.0020

6

hsa05161

Hepatitis B

5.14E-05

0.0031

8

hsa05202

Transcriptional misregulation in cancer

0.0002

0.0106

8

hsa05210

Colorectal cancer

0.0002

0.0106

5

hsa05224

Breast cancer

0.0004

0.0135

7

hsa05205

Proteoglycans in cancer

0.0005

0.0174

8

hsa04630

Jak-STAT signaling pathway

0.0006

0.0174

7

hsa04350

TGF-beta signaling pathway

0.0010

0.0274

5

hsa04380

Osteoclast differentiation

0.0013

0.0321

6

hsa04550

Signaling pathways regulating pluripotency of stem cells

0.0019

0.0432

6

hsa04320

Dorso-ventral axis formation

0.0021

0.0447

3

hsa05216

Thyroid cancer

0.0023

0.0463

3