Table 4 Subtype classification performance using top five FFLs of each category.

NSE TRF

FFL1

MAFA, miR-519d-3p, MCF2L

0.98

0.96

0.96

0.97

FFL2

NANOG, miR-520e, DCAF5

0.94

0.96

0.95

0.95

FFL3

MAFA, miR-96-5p, ARHGAP24

0.98

0.96

0.95

0.97

FFL4

TFAP2C, miR-520d-3p, LYPD6

0.98

1.00

1.00

0.99

FFL5

TFAP2C, miR-519d-3p, LYPD6

0.98

1.00

1.00

0.99

NSE TAF

FFL1

NR2F2, miR-96-5p, ARHGAP24

0.61

0.77

0.70

0.70

FFL2

NR2F2, miR-96-5p, SPATS2L

0.63

0.75

0.68

0.69

FFL3

NR2F1, miR-96-5p, SPATS2L

0.65

0.77

0.71

0.71

FFL4

NR2F2, miR-520e, DCAF5

0.94

0.92

0.91

0.93

FFL5

NR2F2, miR-520d-3p, DCAF5

0.95

0.91

0.90

0.93

NSE MRF

FFL1

ARID5B, miR-367-3p, NFIX

0.97

0.97

0.96

0.97

FFL2

NR2F2, miR-520e, DCAF5

0.94

0.92

0.91

0.93

FFL3

NR2F2, miR-520b, DCAF5

0.95

0.91

0.90

0.93

FFL4

NR2F2, miR-520c-3p, DCAF5

0.94

0.91

0.90

0.93

FFL5

ARID5B, miR-367-3p, STARD13

0.98

0.98

0.98

0.98

SE TRF

FFL1

SPI1, miR-338-3p, ZBTB39

0.86

0.94

0.92

0.90

FFL2

KLF4, miR-200c-3p, RND3

0.88

0.96

0.95

0.92

FFL3

SPI1, miR-142-5p, ULK1

0.90

0.96

0.95

0.93

FFL4

SPI1, miR-29b-3p, CSPG4

0.62

0.71

0.65

0.67

FFL5

SPI1, miR-29b-3p, MEX3B

0.85

0.90

0.88

0.87

SE TAF

FFL1

SPI1, miR-373-3p, PLXDC2

0.83

0.92

0.90

0.87

FFL2

JUN, miR-200c-3p, RND3

0.89

0.96

0.96

0.93

FFL3

SPI1, miR-141-3p, HNMT

0.94

0.93

0.92

0.93

FFL4

NR2F2, miR-141-3p, EPHA2

0.98

0.98

0.98

0.98

FFL5

SPI1, miR-25-3p, FAM20C

0.91

0.92

0.91

0.92

SE MRF

FFL1

JUN, miR-200c-3p, RND3

0.89

0.96

0.96

0.93

FFL2

GATA3, miR-141-3p, HNMT

0.89

0.93

0.92

0.91

FFL3

NR2F2, miR-302d-3p, EPHA2

0.96

0.98

0.98

0.97

FFL4

NR2F2, miR-302a-3p, TIMP3

0.95

0.91

0.91

0.93

FFL5

NR2F2, miR-302a-3p, EPHA2

0.97

0.96

0.96

0.97