Figure 2

ZIKV-induced mitochondrial dysfunction. (A) Respirometry analysis of MOCK or ZIKV-infected astrocytes after 24 and 48 hpi. (B) Routine respiration, (C) ATP synthesis, (D) Reserve capacity of infected astrocytes at different time points post infection. N = 12 for MOCK and N = 3 for each time point of ZIKV infection. Astrocyte lines used were derived from iPSC lines GM23279A, C15, CF1 and CF2.