Figure 1

Median (25^th–75^th IQR) through-focus curves of controls (n = 20) (a), right eye of KCE cohort (n = 12) under unaided viewing (b) and with RGP contact lens (c) obtained by plotting logNS for each value of induced myopia and hyperopia. In this figure and in Fig. 3, induced myopia is indicated as positive numbers while induced hyperopia is indicated as negative numbers along the abscissa. The solid circles indicate individual data points while the curve indicates interpolated data. The lower and the upper thin curves indicate 25th and 75th interquartile range of the through-focus curve, respectively. Horizontal arrow indicates peak IQ, solid and dashed vertical arrows indicate best focus and depth of focus range, respectively.