Table 1 Cohort demographics.

From: Resting-state connectivity stratifies premanifest Huntington’s disease by longitudinal cognitive decline rate

 

Controls

Pre-HD

N

79

74

Sex (Female)

30

34

Age (mean ± STD)

49 ± 11

42 ± 10

CAG

43 ± 2

CAP

48 ± 8

Expected years to disease onset

11 ± 4 (minimum: 5)

  1. CAG: number of CAG repeats in the HTT gene. CAP: CAG-age-product66, a measure of disease burden given by the product of a subject’s number of excess CAG repeats and their age. Here we use the formula CAP = 100 × AGE × [(CAG − 35.5) ÷ 627], i.e. normalized so that score at disease onset (diagnosis based on motor symptoms) is approximately 100.