Table 2 Model accuracies.

From: Resting-state connectivity stratifies premanifest Huntington’s disease by longitudinal cognitive decline rate

Task

AUC

p-value

Spearman’s rho

p-value

SDMT

0.73

0.0023

0.41

0.00005

Cancelation

0.73

0.002

0.27

0.005

Paced tap

0.70

0.008

0.05

0.2977

Grip variability

0.61

0.07

0.07

0.26453

Stroop

0.59

0.136

0.17

0.04877

Count backwards

0.54

0.314

0.08

0.19927

Spot change

0.52

0.396

0.01

0.4807

Mental rotation

0.51

0.439

−0.01

0.54327

Map search

0.47

0.665

−0.01

0.52993

Indirect circle trace

0.36

0.97

−0.14

0.93302

  1. Summary of AUC for classifications between fast-declining and stable subjects (extreme subgroups, subject numbers in Supplementary Table S5) using single tasks (permutation test). The Spearman rank correlation corresponds to the distance between the decision hyperplane and cognitive slopes using all pre-HD subjects from the test sites (within-site permutation test, see Methods).
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