Figure 4 | Scientific Reports

Figure 4

From: A CRISPR/Cas13-based approach demonstrates biological relevance of vlinc class of long non-coding RNAs in anticancer drug response

Figure 4

Analysis pipeline of the survival challenge experiments. The analysis can be subdivided into 3 levels — (1) individual gRNA, (2) gRNA targeting-mismatch pair and (3) whole transcript. Dn and NDn represent normalized gRNA counts in respectively paired +Dox and −Dox samples treated with the same drugs while D and ND represent the corresponding values in log2 space. T and MT refer correspondingly to the targeting and cognate mismatch control gRNAs.

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