Figure 5 | Scientific Reports

Figure 5

From: A CRISPR/Cas13-based approach demonstrates biological relevance of vlinc class of long non-coding RNAs in anticancer drug response

Figure 5

Summary of the positive transcripts identified from the CRISPR/Cas13 survival challenge assays. (a–d) T − MT metrics (a,b) and p-values (c,d) for the indicated genes and vlincRNAs are shown for the imatinib (I) (blue circles), mirin (M) (green circles) and etoposide (E) (red circles) treatments in which the transcripts were found significant. (c,d) The dashed lines represent the adjusted p-values of 0.05. The IDs of the vlincRNAs correspond to the Supplementary Table S1 (tab “Non_overlapping_human_vlincRNAs”) of St. Laurent et al.24 and their coordinates are also listed in Supplementary Table 2 of this study.

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