Table 1 Demographics and clinical characteristics of the patients at baseline.
From: Gene-Related Response of Basal Cell Carcinoma to Biologic Treatment with Vismodegib
Characteristics | Locally advanced BCC (N = 12) | Localised BCC (N = 22) |
|---|---|---|
Age (y), mean ± SD (range) | 79.1 ± 8.1 (60–88) | 71.5 ± 14.4 (38–90) |
Sex | ||
Male | 6 (50%) | 16 (72.7%) |
Female | 6 (50%) | 6 (27.3%) |
Tumor location | ||
Head and neck | 10 (83%) | 14 (63.6%) |
Trunk and limbs | 2 (17%) | 8 (36.4%) |
Contraindication for surgery | N/A | |
Inoperable tumor | 3 (33.3%) | |
Substantial morbidity or deformity anticipated | 6 (66.7%) | |
Response to treatment | N/A | |
Complete response | 6 (55.5%) | |
Partial response | 4 (36.4%) | |
No response | 1 (9.1%) | |
