Figure 4

Risk of second cancer relative to 2F-IMRT based on the full mechanistic dose-response model. *Indicates no statistical difference; †indicates significantly lower for alternative techniques compared to 2F-IMRT; ‡indicates significantly higher for alternative techniques compared to 2F-IMRT; indicates a statistically significant difference between treatment plans. CB = contralateral breast; CL = contralateral lung; and IL = ipsilateral lung. W-TF = 3D-CRT with two tangential fields and wedges; 2F-IMRT = IMRT with two tangential fields; 6F-IMRT = IMRT with six fields; and VMAT = VMAT with double partial arcs.