Figure 4
From: Large deletions in immunoglobulin genes are associated with a sustained absence of DNA Polymerase η
XP-V patients over 50 years of age present higher frequency of large deletions (larger than 10 bp) compared to age-matched controls. (A) Size of deletions (in base pairs) of XP-V patients (older than 50 years) and controls of the French cohort. Mid age: younger than 50 years. Old age: older than 50 years. ***p < or = 0.0005 (1-way Anova test). Each color represents one patient/control. (B) Size of insertions of XP-V patients (older than 50 years) and controls of the French cohort. Each color represents one patient/control. (C) Number of large deletions (larger than 20 bp) was plotted against age (years) of XP-V patients and controls of the Brazilian cohort. Values of Pearson correlation (R) and p values are indicated for each group (XP-V and controls).
