Figure 2 | Scientific Reports

Figure 2

From: Calponin-3 deficiency augments contractile activity, plasticity, fibrogenic response and Yap/Taz transcriptional activation in lens epithelial cells and explants

Figure 2

Distribution of CNN3 to the actin stress fibers, lateral membranes and primary cilia in mouse lens epithelial cells and explants. (A) CNN3 exhibits a stress-fiber like intense cortical distribution (green immunofluorescence; arrows), colocalizing with F-actin (red TRITC-phalloidin staining) in mouse lens epithelial primary cell cultures. (B) In mouse lens epithelial explants, CNN3 distributes (green immunofluorescence) to the epithelial lateral membranes (long arrows) and primary cilia (short arrows) where it colocalizes with F-actin (red TRITC-phalloidin staining). Inserts show magnified images of a small region of the same specimen. Merged images are used to indicate colocalization between CNN3 and F-actin. Scale bars indicate image magnification.

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