Table 1 Antifungal susceptibility of antifungal agents against C. auris.

From: Improved efficacy of antifungal drugs in combination with monoterpene phenols against Candida auris

Candida sp.

Test agents

MIC values in µg/ml (n = 3)

Interpretation No. of isolates (%)

Median (range)

S

R

C. auris (25)

Fluconazole

125 (16–500)

3 (12)

22 (88)

Amphotericin B

0.5 (0.125–4)

20 (80)

5 (4)

Nystatin

2 (0.5–4)

12 (48)

13 (52)

Caspofungin

0.25 (0.125–2)

24 (96)

1 (4)

C. albicans (1)

Fluconazole

4 (4–8)

1 (100)

0 (0)

Amphotericin B

0.125 (0.125–0.25)

1 (100)

0 (0)

Nystatin

0.5 (0.25–1)

1 (100)

0 (0)

Caspofungin

0.125 (0.125)

1 (100)

0 (0)

  1. S: sensitive; R: resistant.
  2. Classification based on CDC guidelines (Tentative MIC Breakpoints); Fluconazole (S < 32 µg/ml; R ≥ 32 µg/ml); Amphotericin B (S < 2 µg/ml; R ≥ 2); Nystetin (S < 2 µg/ml; R ≥ 2) Caspofungin (S < 2 µg/ml; R ≥ 2).