Table 2 Antifungal activity of phenolic compounds against C. auris.
From: Improved efficacy of antifungal drugs in combination with monoterpene phenols against Candida auris
Candida sp. | Test agents | MIC values in µg/ml (n = 3) | MFC values in µg/ml (n = 3) |
|---|---|---|---|
Median (range) | Median (range) | ||
C. auris (25) | Carvacrol | 125 (63–250) | 250 (250–500) |
Thymol | 312 (156–625) | 1250 (625–1250) | |
Eugenol | 625 (312–1250) | 2500 (625–2500) | |
Methyl eugenol | 1250 (625–1250) | 2500 (≥2500) | |
C. albicans (1) | Carvacrol | 250 (250) | 500 (500) |
Thymol | 625 (312–625) | 1250 (625–1250) | |
Eugenol | 625 (625–1250) | 1250 (1250–2500) | |
Methyl eugenol | 1250 (625–1250) | 2500 (≥2500) |
