Figure 1

Model schematic. The model was initiated with a cohort of individuals waiting to receive an organ. People in the model could die while on the waiting list, from complications after receiving a transplant or from age-dependent all-cause mortality. When past or current HCV infection was removed as a donor exclusion criterion, transplant waiting times were decreased and individuals could end up chronically infected post-transplant if: the donor had been exposed, the donor was chronically infected, the infection was transmitted during transplant and the recipient failed to spontaneously clear or respond to prophylactic HCV treatment. People who ended up with a chronic HCV infection post-transplant could develop advanced liver disease, increasing their mortality risks.