Figure 4
From: Near-Infrared Fluorescent pH Responsive Probe for Targeted Photodynamic Cancer Therapy

Photodynamic therapy effect of I2-IR783-Mpip. Relative viabilities of HepG2 cells in media (A) pH 5.0 and (B) pH 7.4; red bars represent cells irradiated with 850 lamp, blue bars represent cells covered by 5 mm pork tissue with 850 nm light irradiation and black bars represent cells without irradiation. (C) LIVE/DEAD viability/cytotoxicity assay of I2-IR783-Mpip under dark and light conditions at various concentrations (0, 20 and 50 µM). Scale bars = 100 μm. Statistical analysis are based on one-way ANOVA followed by Tukey’s post-hoc analysis (*P < 0.05, **P < 0.01, ***P < 0.001).