Figure 2
From: Down Syndrome Reduces the Sedative Effect of Midazolam in Pediatric Cardiovascular Surgical Patients

Relationship between operation severity and sedative dosage. The figure shows the relationship between operation risk score measured by RACHES-1 and sedative dosage. Category 1 operations tended to not differ in total amounts of sedative, but Category 2 and Category 3 had a high probability that DS patients would need a higher total amount of sedative (the probability of the DS group dosage of midazolam was greater than normal: Category 1 = 0.57, Category 2 = 0.99, Category 3 = 0.98; the probability of the DS group dosage of dexmedetoimidine was greater than normal: Category 1 = 0.84, Category 2 = 0.95, Category 3 = 0.92).