Figure 5

(A) Effects of scutellarin on rosuvastatin uptake in rat primary hepatocytes, (B) in OATP1B1-HEK293T cells and (C) The uptake of rosuvastatin in OATP1B1-HEK293T cells vs MOCK-HEK293T cell (n = 3, mean ± standard deviation). Compared groups: rosuvastatin treatment vs. combination treatment (rosuvastatin + scutellarin), *indicates difference compared with the rosuvastatin alone group statistically (P < 0.05), **indicates great difference compared with the rosuvastatin alone group (P < 0.01).