Table 2 Adjusted hazard ratios for incident PD according to serum GGT activity.

From: Serum gamma-glutamyltransferase activity and Parkinson’s disease risk in men and women

GGT

(n)

Male

Female

Q1

(701,522)

Q2

(719,273)

Q3

(734,048)

Q4

(720,444)

Q1

(848,532)

Q2

(744,609)

Q3

(847,154)

Q4

(782,823)

Incident PD (n)

2,984

2,624

2,258

1,646

2,304

2,458

3,274

3,347

aIncidence rate

66.6

57.2

48.3

35.9

42.5

51.6

60.4

66.8

HR (95% CI)

bModel I

1

0.97

(0.92,1.02)

0.84

(0.80,0.89)

0.67

(0.63,0.71)

1

1.16

(1.10,1.23)

1.25

(1.18,1.31)

1.33

(1.26,1.40)

cModel II

1

0.97

(0.92,1.02)

0.87

(0.82,0.92)

0.72

(0.67,0.76)

1

1.15

(1.08,1.21)

1.21

(1.15,1.28)

1.30

(1.23,1.37)

  1. aPD incidence per 1,000 person-years, badjusted for age, cadjusted for age, BMI, income, smoking, alcohol drinking, and exercise; income categorized as the lower quartile of income and the others; smoking and alcohol drinking as yes or no; doing exercise defined as at least 20 minutes ≥1 time/week.
  2. PD, Parkinson disease; GGT, gamma-glutamyltransferase; HR, hazard ratio; CI, confidence interval; Q1, quartile 1; Q2, quartile 2; Q3, quartile 3; Q4, quartile 4.
Back to article page