Figure 3 | Scientific Reports

Figure 3

From: Comparative study of the interactions between fungal transcription factor nuclear localization sequences with mammalian and fungal importin-alpha

Figure 3

Schematic diagram of the interactions between the NIT-2 NLS, PAC-3 NLS and SV40 NLS peptides and the minor and major binding sites of MmImpα and NcImpα. (A) MmImpα/NIT-2 NLS - major binding site. (B) MmImpα/NIT-2 NLS - minor binding site. (C) NcImpα/NIT-2 NLS51- major binding site. (D) NcImpα/NIT-2 NLS - minor binding site. (E) MmImpα/PAC-3 NLS - major binding site. (F) MmImpα/PAC-3 NLS - minor binding site. (G) MmImpα/SV40 NLS - major binding site. (H) MmImpα/SV40 NLS - minor binding site. The peptide backbones are drawn in cyan (MmImpα/NIT-2 NLS), orange (NcImpα/NIT-2 NLS), brown (MmImpα/PAC-3 NLS) or violet (MmImpα/SV40 NLS) with the residues identified by the one-letter code. The Impα side-chain residues interacting with the peptide are indicated with their names and different colors. The polar contacts are shown with dashed lines, and the hydrophobic contacts are indicated by arcs with radiating spokes. This figure was generated using PyMOL v.1.8.664 program.

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