Figure 1
From: Islet-1 synergizes with Gcn5 to promote MSC differentiation into cardiomyocytes

Co-IP experiments confirmed that islet-1 and Gcn5 bound together during MSC differentiation into cardiomyocytes induced by islet-1 overexpression. Islet-1 and IgG antibodies were chosen to pull down proteins, and the islet-1 and Gcn5 bands were then detected by Western blot. Gcn5 was detected in proteins pulled down by the islet-1 antibody, which indicated that islet-1 could form a complex with Gcn5.