Table 5 Macular sectors’ (ETDRS regions) thickness differences among diagnostic groups.

From: Evaluation of macular thickness and volume tested by optical coherence tomography as biomarkers for Alzheimer’s disease in a memory clinic

Group (N)

Mean

SD

Meanaa

SEM

ETDRS Center p = 0.735

Control (414)

247.82

22.52

246.29aa

1.48

MCI (192)

246.76

25.59

246.89aa

1.91

AD (324)

243.19

30.03

245.08aa

1.61

ETDRS Inner-Temporal p = 0.125

Control (414)

299.92

16.03

296.04aa

1.10

MCI (192)

293.86

19.97

295.30aa

1.42

AD (324)

288.50

23.59

292.70aa

1.20

ETDRS Inner-Superior p = 0.040

Control (414)

312.45

16.22

307.81aa

1.12

MCI (192)

306.04

20.08

308.21aa

1.44

AD (324)

299.45

24.29

304.12aa

1.22

ETDRS Inner-Nasal p = 0.040

Control (414)

313.25

17.30

309.43aa

1.14

MCI (192)

306.00

21.21

307.53aa

1.47

AD (324)

300.75

23.35

304.74aa

1.24

ETDRS Inner-Inferior p = 0.095

Control (414)

309.88

16.22

305.44aa

1.12

MCI (192)

303.72

20.36

305,70aa

1.44

AD (324)

297.71

24.06

302.24aa

1.22

ETDRS Outer-Temporal p = 0.683

Control (414)

252.95

16.95

249.78aa

1.05

MCI (192)

248.50

18.13

249.81aa

1.35

AD (324)

245.24

20.85

248.54aa

1.14

ETDRS Outer-Superior p = 0.306

Control (414)

268.68

14.84

264.59aa

0.94

MCI (192)

264.31

17.20

266.51aa

1.24

AD (324)

260.31

20.01

264.25aa

1.05

ETDRS Outer-Nasal p = 0.397

Control (414)

285.41

17.711

281.18aa

1.04

MCI (192)

281.28

18.226

283.61aa

1.34

AD (324)

278.55

20.230

282.60aa

1.13

ETDRS Outer-Inferior p = 0.819

Control (414)

258.07

14.391

254.62aa

0.95

MCI (192)

253.72

16.979

255.57aa

1.23

AD (324)

251.43

19.813

254.78aa

1.04

  1. Different raw and adjusted macular thickness (μm), standard deviation (SD), and standard error of the mean (SEM). After a multivariate adjustment, significant differences between diagnostic groups have appeared in the superior and nasal areas of the inner ring. After a correction for multiple comparisons, no significant differences among diagnostic groups were detected. Dispersion is shown as SEM.