Figure 3 | Scientific Reports

Figure 3

From: Staphylococcus Aureus Osteomyelitis as an Inducer of Tolerance to Escherichia Coli Pyelonephritis: an Experimental Study

Figure 3

Modulation of the phagocytic potential in tissues Rabbits were divided into three groups: S subject to sham osteomyelitis followed three weeks later by sham pyelonephritis; P: subject to sham osteomyelitis followed three weeks later by Escherichia coli pyelonephritis; and OP: subject to Staphylococcus aureus osteomyelitis followed three weeks later by E. coli pyelonephritis. (A) Tissue outgrowth of Escherichia coli; p vales of comparisons between the P and the OP groups are provided. In all animals of the S group outgrowth was below the lower limit of detection. (B) Tissue concentrations of myeloperoxidase (MPO); The p values of the significant comparisons are provided: a0.018 vs the respective values of the right kidney; b0.002 group S vs group P; c < 0.0001 group S vs group OP; d0.015 group P vs group OP. (C) Correlation between bacterial outgrowth and MPO in the spleen; the Spearman’s coefficient of correlation and the p-value of significance are provided for each group. D) Correlation between bacterial outgrowth and MPO in the right kidney; the Spearman’s coefficients of correlation and the p-values of significance are provided for each group.

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