Figure 1 | Scientific Reports

Figure 1

From: Antiviral activity of iridoid glycosides extracted from Fructus Gardeniae against influenza A virus by PACT-dependent suppression of viral RNA replication

Figure 1

Antiviral activity of IGEs in Madin-Darby canine kidney (MDCK) cells infected with influenza A virus. (A) Cytopathic effect (CPE) observed in MDCK cells. There was no CPE in cell control group. Typical CPE characteristics, cell rounding and crimpling were observed in the virus control group, but were significantly alleviated in the ribavirin group and the IGEs treatment group. (B) MDCK cell viability of cells was evaluated by MTT assay. Each value was expressed as the mean ± SEM(n = 4). **P < 0.01 compared to the cell control group, ##P < 0.01 and #P < 0.05 compared to the virus control group. (C) The value of virus titres for each group represented. Virus titres are shown as -lgTCID50 and expressed as the mean ± SEM (n = 6). **P < 0.01 compared to the cell control group, and ##P < 0.01 compared to the virus control group.

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