Table 1 Clinical parameters before and after propensity score matching (model 1).

From: Corticosteroid reduction by addition of cetirizine and montelukast in biopsy-proven minimal-change nephrotic syndrome concomitant with allergic disorders

 

Before matching

After matching (model 1)

Treatment (n = 13)

Control (n = 38)

Stand diff

Treatment (n = 13)

Control (n = 13)

Stand diff

*Age at inclusion, years

48.2 ± 14.0

54.8 ± 17.3

−0.42

48.2 ± 14.0

51.3 ± 17.2

−0.20

*Sex prevalence, no. of men %

7, 54%

25, 68%

−0.28

7, 54%

9, 69%

0.32

*eGFR at inclusion, ml/min/1.73 m2

86 ± 23

76 ± 17

0.49

86 ± 23

85 ± 11

0.09

*Urinary protein at inclusion, g/gCre

0.07 ± 0.12

0.12 ± 0.35

−0.19

0.07 ± 0.12

0.05 ± 0.07

0.20

Age at onset, years

31.1 ± 19.0

38.7 ± 19.0

−0.40

31.1 ± 19.0

35.0 ± 20.0

−0.20

Disease duration, months

205 ± 114

192 ± 156

0.09

205 ± 114

197 ± 112

0.09

Past relaplse, times

4.2 ± 3.3

2.7 ± 4.1

0.38

4.2 ± 3.3

4.3 ± 5.0

−0.04

*past relapse per year, times/yr

0.29 ± 0.19

0.15 ± 0.19

0.72

0.29 ± 0.19

0.27 ± 0.25

0.10

*Follow up period, months

44.6 ± 4.8

56.6 ± 10.2

−1.50

44.6 ± 4.8

54.7 ± 12.4

−1.07

*Other immunosupressants, no./%

6, 46%

10, 27%

0.41

6, 46%

7, 54%

−0.15

*Comcomitant allergic disorders, no./%

13, 100%

20, 54%

1.30

13, 100%

13, 100%

0.00

Dyslipedemia, no./%

1, 8%

14, 38%

−0.77

1, 8%

2, 15%

−0.24

*minimum PSL dose, mg

0.83 ± 1.1

2.6 ± 2.9

−0.37

0.83 ± 1.1

1.08 ± 2.7

−0.12

*PSL dose at baseline, mg

4.1 ± 3.7

3.3 ± 3.7

0.21

4.1 ± 3.7

4.1 ± 3.8

0.00

IgE, U/mL

780 ± 643

496 ± 592

0.46

780 ± 643

865 ± 676

−0.13

Eosinophil,/microL

80 ± 62

224 ± 198

−0.98

80 ± 62

258 ± 200

−1.20

Infection, irregular PSL reduction, or malignancy, no./%

4, 31%

16, 42%

−0.26

4, 31%

3, 23%

0.17

  1. Values are presented as median ± standard deviation.
  2. Stand diff, standardized difference; eGFR, estimated glomerular filtration rate; PSL, prednisolone; Cre, creatinine; *indicates items that were matched using the propensity-score analysis. *matched items.