Figure 9 | Scientific Reports

Figure 9

From: Hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitors induce autophagy and have a protective effect in an in-vitro ischaemia model

Figure 9

Representative double merged (FITC labelled neuron specific Tuj1 and DAPI stained nuclei) immunofluorescence images of primary rat neurons following FG4592 and DMOG treatment in normoxia. No morphological changes were observed with FG4592 treatment (10–100 µM) and DMOG (100, 250 µM), but DMOG (500 µM, 1 mM and 2 mM) treatment resulted in neurons with shorter and fewer neurites and reduced cell densities per microscopic field.

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