Table 3 Subgroup analysis of crude and adjusted hazard ratios (95% confidence interval) of sudden sensory neural hearing loss in depression according to age and sex in study I.

From: Bidirectional relation between depression and sudden sensorineural hearing loss: Two longitudinal follow-up studies using a national sample cohort

Characteristics

HRs of SSNHL

Crude†

P-value

Adjusted†‡

P-value

Young men (20–39 years old, n = 33,400)

Depression

1.17 (0.71–1.93)

0.531

0.99 (0.60–1.64)

0.967

Control I

1.00

 

1.00

 

Young women (20–39 years old, n = 63,715)

Depression

1.20 (0.85–1.70)

0.311

1.08 (0.76–1.53)

0.688

Control I

1.00

 

1.00

 

Middle aged men (40–59 years old, n = 40,510)

Depression

1.39 (1.00–1.92)

0.047*

1.22 (0.88–1.70)

0.229

Control I

1.00

 

1.00

 

Middle aged women (40–59 years old, n = 78,620)

Depression

1.54 (1.25–1.90)

<0.001*

1.36 (1.10–1.68)

0.005*

Control I

1.00

 

1.00

 

Old men (60 + years old, n = 29,615)

Depression

1.05 (0.69–1.58)

0.832

0.92 (0.61–1.40)

0.709

Control I

1.00

 

1.00

 

Old women (60 + years old, n = 57,730)

Depression

1.24 (0.86–1.47)

0.386

1.03 (0.79–1.34)

0.836

Control I

1.00

 

1.00

 
  1. *Cox-proportional hazard regression model, Significance at P Co0.05.
  2. †Stratified model for age, sex, income, and region of residence.
  3. ‡Adjusted model for Charlson Comorbidity Index.
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