Figure 7
From: Structural basis for Glycan-receptor binding by mumps virus hemagglutinin-neuraminidase
3D model of MuV-HN in complex with undecasaccharide 2. (a) Close up view of ligand 2 binding mode at the MuV-HN active site, drawn by using Pymol 2.3 Software (https://pymol.org/2/). The main amino acid residues involved in the binding are represented in stick. Galactose and N-acetyl Glucosamine residues are depicted in yellow and blue, respectively. (b) Two-dimensional plot illustrating the interactions of the sialylated undecasaccharide 2 with the residues in the binding pocket of MuV-HN derived by a tool included in Maestro Version 10.5.014 (https://www.schrodinger.com/maestro). Dotted arrows represent hydrogen bonds with functional groups from side chains and solid arrows such with functional groups of the backbone. The residues shown, close to the ligand, are involved into hydrophobic and polar interactions.
