Figure 2
From: Obeticholic acid and INT-767 modulate collagen deposition in a NASH in vitro model
Activation of HSCs. (a) ACTA2 mRNA expression upon FFAs exposure vs. CTRL. (b) ACTA2 expression following treatment with FFAs and FXR agonists vs. FFAs (dashed bar). (c) ACTA2 expression following OCA and INT-767 treatment vs. CTRL (dashed line). Data is represented as mean ± SD of at least three independent biological replicates. *p < 0.05; **p < 0.01 vs. FFAs (b) or CTRL (c).
