Table 3 Statistics for the responses of SlitOR25 to known (acetophenone, benzyl alcohol and benzaldehyde) and new ligands at different doses. Solvent: ethanol.
From: Machine learning decodes chemical features to identify novel agonists of a moth odorant receptor
Tested molecules | Dilutions | |||||
|---|---|---|---|---|---|---|
10−7 | 10−6 | 10−5 | 10−4 | 10−3 | 10−2 | |
Acetophenone | NS | *** | *** | *** | *** | *** |
Benzyl alcohol | NS | NS | NS | *** | *** | *** |
Benzaldehyde | NS | *** | *** | *** | *** | *** |
2′-Fluoroacetophenone | NS | *** | *** | *** | *** | *** |
2-Fluorobenzaldehyde | NS | NS | NS | *** | *** | *** |
2-Fluorobenzyl alcohol | NS | NS | *** | *** | *** | *** |
3-Fluorobenzaldehyde | NS | * | *** | *** | *** | *** |
2,6-Difluorobenzaldehyde | *** | *** | *** | *** | *** | *** |
p-Tolualdehyde | NS | NS | *** | *** | *** | *** |
4′-Fluoroacetophenone | NS | *** | *** | *** | *** | *** |
2′,4′-Difluoroacetophenone | *** | *** | *** | *** | *** | *** |
