Table 1 Baseline clinical and laboratory characteristics of study participants.

From: Left atrial dysfunction in sickle cell anemia is associated with diffuse myocardial fibrosis, increased right ventricular pressure and reduced exercise capacity

Characteristic

Value

Age (yr)

23.0 ± 10.4

BSA (m2)

1.69 ± 0.3

Female, n (%)

13 (54)

Receiving hydroxyurea, n (%)

19 (79)

Baseline Heart rate (bpm)

74 ± 10

Systolic blood pressure (mmHg)

118 ± 11

Diastolic blood pressure (mmHg)

67 ± 8

White blood cell count (103/mm3)

9.6 ± 3.6

Hemoglobin (g/dL)

9.9 ± 1.4

Mean corpuscular volume (fL)

94 ± 19

Reticulocyte count (%)

8.1 ± 5.2

Platelet count (103/mm3)

343 ± 98

Bilirubin (mg/dL)

2.4 ± 1.5

AST (unit/L)

48 ± 29

LDH (unit/L)

550 ± 271

Plasma free hemoglobin (mg/dL)

26 (11–105)

Creatinine (mg/dL)

0.57 ± 0.17

Cystatin C (mg/L)

0.64 ± 0.13

GFR (mL/min/1.73 m2)

145 ± 38

NT-proBNP (pg/mL)

55 (23–150)

Native T1 (ms)

1005 ± 67

ECV

0.44 ± 0.08

% Predicted maximum oxygen consumption

57 ± 12

VE/VCO2 slope at maximum exercise

30 ± 7

  1. The values are reported as mean ± standard deviation or median (interquartile range). AST: aspartate aminotransferase, ECV: extracellular volume, GFR: glomerular filtration rate, LDH: lactate dehydrogenase, min: minute, VO2: oxygen consumption, VCO2: carbon dioxide production, yr: year.
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