Figure 1 | Scientific Reports

Figure 1

From: Author Correction: Notch signaling pathway is a potential therapeutic target for extracranial vascular malformations

Figure 1

DAPT and RO4929097 effectively inhibit Notch signaling without altering cell viability. (A,B) Measurement of HUVEC (A) and hLEC (B) cell viability after GSI treatments. Quantitative data are represented as mean ± SEM. n = 3 for HUVEC and hLEC. Significance was determined by 2-tailed, type 2 Student’s t test, *P < 0.05. (C,D) Relative expression of downstream Notch target gene Hey1 in GSI-treated HUVEC (C) and hLEC (D). Quantitative data are represented as mean values of fold change over DMSO control ± SEM. n = 4 for each cell line. Gapdh and β-actin were used as housekeeping control. Significance was determined by 2-tailed, type 2 Student’s t test, *P < 0.05, **P < 0.01.

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