Table 4 Subgroup analyses of crude and adjusted hazard ratios (95% confidence interval) of peptic ulcer for depression according to age and sex.

From: Reciprocal association between depression and peptic ulcers: Two longitudinal follow-up studies using a national sample cohort

Characteristics

Hazard ratios for depression

Crude†

P-value

Adjusted†‡

P-value

Age <40 years old, men (n = 37,740)

   Peptic ulcer

1.70 (1.48–1.95)

<0.001*

1.54 (1.34–1.77)

<0.001*

   Control II

1.00

 

1.00

 

Age <40 years old, women (n = 40,734)

   Peptic ulcer

1.77 (1.62–1.95)

<0.001*

1.61 (1.47–1.77)

<0.001*

   Control II

1.00

 

1.00

 

Age 40–59 years old, men (n = 59,256)

   Peptic ulcer

1.95 (1.77–2.15)

<0.001*

1.75 (1.59–1.93)

<0.001*

   Control II

1.00

 

1.00

 

Age 40–59 years old, women (n = 59,528)

   Peptic ulcer

1.89 (1.77–2.02)

<0.001*

1.72 (1.61–1.84)

<0.001*

   Control II

1.00

 

1.00

 

Age ≥60 years old, men (n = 27,214)

   Peptic ulcer

1.91 (1.70–2.14)

<0.001*

1.75 (1.56–1.96)

<0.001*

   Control II

1.00

 

1.00

 

Age ≥60 years old, women (n = 30,708)

   Peptic ulcer

1.77 (1.64–1.92)

<0.001*

1.60 (1.48–1.73)

<0.001*

   Control II

1.00

 

1.00

 
  1. *Cox-proportional hazard regression model, Significance at P < 0.05.
  2. †Stratified model for age, sex, income, and region of residence.
  3. ‡Adjusted model for Charlson Comorbidity index calculated without peptic ulcer.
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