Figure 5
From: Identification and characterization of a bacterial core methionine synthase
Computational model of the active site of core-MetECBDB from Dehalococcoides mccartyi strain CBDB1. His122 is tuned towards the active site of the protein where a zinc atom is coordinated by His215, Cys217 and Cys312. His122 might replace the dimethylbenzimidazole moiety of cobalamin in the “bae-off/His-on” mode. The structure was calculated with the I-TASSER server65 and visualized with PyMOL66.
