Table 5 HLA Conserved Extended Haplotypes* (CEH) in 218 Lacandon Native Americans.
From: Diversity of HLA Class I and Class II blocks and conserved extended haplotypes in Lacandon Mayans
Conserved extended haplotype (CEH) | H.F. | n (N = 218) | Δ′ | p | t |
|---|---|---|---|---|---|
B*40:02~C*03:04~DRB1*04:11~DQB1*03:02 | 0.1702 | 74 | 0.6663 | <0.0001 | 15.4 |
B*35:12~C*04:01~DRB1*04:11~DQB1*03:02 | 0.0759 | 33 | 0.5328 | <0.0001 | 7.9 |
B*39:05~C*07:02~DRB1*04:07~DQB1*03:02 | 0.0759 | 33 | 0.2992 | <0.0001 | 7.4 |
B*35:01~C*07:02~DRB1*04:11~DQB1*03:02 | 0.0575 | 25 | −0.0679 | 0.6306 | −0.7 |
B*35:01~C*07:02~DRB1*16:02~DQB1*03:01 | 0.0483 | 21 | 0.6710 | <0.0001 | 8.9 |
B*40:08~C*03:04~DRB1*04:07~DQB1*03:02 | 0.0460 | 20 | 0.5985 | <0.0001 | 7.8 |
B*39:05~C*07:02~DRB1*04:11~DQB1*03:02 | 0.0414 | 18 | −0.3102 | 0.0306 | −3.1 |
B*35:01~C*07:02~DRB1*04:07~DQB1*03:02 | 0.0368 | 16 | −0.0478 | 0.8076 | −0.4 |
B*40:02~C*03:04~DRB1*14:02~DQB1*03:01 | 0.0345 | 15 | 0.4677 | <0.0001 | 6.2 |
B*35:01~C*04:01~DRB1*04:04~DQB1*03:02 | 0.0322 | 14 | 0.6416 | <0.0001 | 7.5 |
B*40:02~C*15:02~DRB1*14:06~DQB1*03:01 | 0.0322 | 14 | 0.8699 | <0.0001 | 7.7 |
B*18:01~C*07:01~DRB1*11:04~DQB1*03:01 | 0.0253 | 11 | 0.8417 | <0.0001 | 6.8 |
B*39:05~C*07:02~DRB1*16:02~DQB1*03:01 | 0.0161 | 7 | 0.0999 | 0.1982 | 2.0 |
B*35:12~C*04:01~DRB1*04:07~DQB1*03:02 | 0.0138 | 6 | −0.4378 | 0.0859 | −3.1 |
B*39:05~C*07:02~DRB1*08:02~DQB1*04:02 | 0.0115 | 5 | 0.0332 | 0.6805 | 0.7 |
B*40:02~C*03:05~DRB1*04:07~DQB1*03:02 | 0.0115 | 5 | 0.5148 | 0.0067 | 3.5 |
B*40:08~C*03:04~DRB1*04:03~DQB1*03:02 | 0.0115 | 5 | 0.5255 | <0.0001 | 4.3 |
B*35:12~C*04:01~DRB1*08:02~DQB1*04:02 | 0.0092 | 4 | 0.0507 | 0.4216 | 1.3 |
B*35:43~C*01:02~DRB1*04:07~DQB1*03:02 | 0.0092 | 4 | 0.7412 | 0.0021 | 3.6 |
B*39:08~C*07:02~DRB1*04:07~DQB1*03:02 | 0.0092 | 4 | 0.5687 | 0.0097 | 3.3 |
B*52:01~C*03:03~DRB1*04:04~DQB1*03:02 | 0.0092 | 4 | 0.7850 | <0.0001 | 4.0 |
B*35:01~C*04:01~DRB1*08:02~DQB1*04:02 | 0.0069 | 3 | 0.0892 | 0.0947 | 2.2 |
B*35:01~C*07:02~DRB1*04:03~DQB1*03:02 | 0.0069 | 3 | 0.2049 | 0.1574 | 2.0 |
B*39:01~C*07:02~DRB1*04:11~DQB1*03:02 | 0.0069 | 3 | 0.2158 | 0.4805 | 1.1 |
B*39:05~C*07:02~DRB1*14:02~DQB1*03:01 | 0.0069 | 3 | −0.2660 | 0.5464 | −1.2 |
B*39:06~C*07:02~DRB1*04:04~DQB1*03:02 | 0.0069 | 3 | 0.4624 | <0.0001 | 3.2 |
B*14:02~C*08:02~DRB1*01:01~DQB1*05:01 | 0.0046 | 2 | 1.0000 | <0.0001 | 2.8 |
B*14:02~C*08:02~DRB1*01:02~DQB1*05:01 | 0.0046 | 2 | 0.6637 | <0.0001 | 2.8 |
B*35:01~C*04:01~DRB1*04:07~DQB1*03:02 | 0.0046 | 2 | −0.5806 | 0.1399 | −2.9 |
B*35:01~C*04:01~DRB1*04:11~DQB1*03:02 | 0.0046 | 2 | −0.7372 | 0.0091 | −4.1 |
B*35:01~C*07:02~DRB1*04:04~DQB1*03:02 | 0.0046 | 2 | −0.6132 | 0.1144 | −3.4 |
B*35:01~C*07:02~DRB1*08:02~DQB1*04:02 | 0.0046 | 2 | −0.5415 | 0.2029 | −2.7 |
B*35:12~C*04:01~DRB1*14:02~DQB1*03:01 | 0.0046 | 2 | −0.2504 | −0.6566 | −0.9 |
B*39:01~C*07:02~DRB1*04:07~DQB1*03:02 | 0.0046 | 2 | 0.1375 | 0.5317 | 1.0 |
B*40:02~C*15:02~DRB1*08:02~DQB1*04:02 | 0.0046 | 2 | 0.0554 | 0.3378 | 1.4 |
B*40:08~C*03:04~DRB1*04:11~DQB1*03:02 | 0.0046 | 2 | −0.8097 | 0.0007 | −5.3 |
B*40:11~C*03:04~DRB1*08:02~DQB1*04:02 | 0.0046 | 2 | 1.0000 | <0.0001 | 2.8 |
B*51:01~C*15:04~DRB1*04:04~DQB1*03:02 | 0.0046 | 2 | 1.0000 | <0.0001 | 2.8 |
B*53:01~C*04:01~DRB1*13:03~DQB1*02:02 | 0.0046 | 2 | 1.0000 | <0.0001 | 2.8 |
Native American MPA CEH frequency: | 0.3188 | ||||
European MPA CEH frequency: | 0.0917 | ||||
African MPA CEH frequency: | 0.0023 | ||||
Asian MPA CEH frequency: | 0.0023 | ||||
Not previously reported CEH frequency: | 0.6055 | ||||
