Table 7 HLA-A~B~C~DRB1~DRB3/4/5~DQB1~DQA1~DPA1~DPB1 haplotypes* in 218 Lacandon Native Americans.
From: Diversity of HLA Class I and Class II blocks and conserved extended haplotypes in Lacandon Mayans
HLA~A~B~C~DRB1~DRB3/4/5~DQB1~DQA1~DPA1~DPB1 haplotype | H.F. | n (N = 218) | Δ′ | p | t |
|---|---|---|---|---|---|
A*31:01~B*40:02~C*03:04~DRB1*04:11~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0667 | 29 | 0.3587 | <0.0001 | 8.3 |
A*31:01~B*40:02~C*03:04~DRB1*04:11~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0529 | 23 | 0.3582 | <0.0001 | 8.3 |
A*68:03~B*35:01~C*07:02~DRB1*16:02~DRB5*02:02~DQB1*03:01~DQA1*05:05~DPA1*01:03~DPB1*04:02 | 0.0414 | 18 | 0.6975 | <0.0001 | 8.7 |
A*24:02~B*35:12~C*04:01~DRB1*04:11~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0368 | 16 | 0.4681 | 0.0000 | 6.6 |
A*68:01~B*39:05~C*07:02~DRB1*04:11~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0345 | 15 | 0.5035 | <0.0001 | 6.5 |
A*02:06~B*35:01~C*07:02~DRB1*04:11~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0299 | 13 | 0.2334 | 0.0040 | 4.2 |
A*68:03~B*39:05~C*07:02~DRB1*04:07~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0299 | 13 | 0.4686 | 0.0000 | 6.4 |
A*24:02~B*40:02~C*15:02~DRB1*14:06~DRB3*01:01~DQB1*03:01~DQA1*05:03~DPA1*01:03~DPB1*04:01 | 0.0253 | 11 | 1.0000 | <0.0001 | 6.8 |
A*68:01~B*40:08~C*03:04~DRB1*04:07~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0230 | 10 | 0.3980 | <0.0001 | 6.0 |
A*02:01~B*18:01~C*07:01~DRB1*11:04~DRB3*02:02~DQB1*03:01~DQA1*05:05~DPA1*01:03~DPB1*04:02 | 0.0161 | 7 | 0.8713 | <0.0001 | 5.4 |
A*02:01~B*35:12~C*04:01~DRB1*04:11~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0161 | 7 | 0.4828 | 0.0006 | 4.3 |
A*02:06~B*35:01~C*07:02~DRB1*04:11~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0161 | 7 | 0.1042 | 0.0777 | 2.6 |
A*68:01~B*40:08~C*03:04~DRB1*04:07~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0138 | 6 | 0.0890 | 0.2238 | 1.9 |
A*24:14~B*35:01~C*04:01~DRB1*04:04~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*02:02~DPB1*05:01 | 0.0115 | 5 | 0.4888 | <0.0001 | 4.5 |
A*02:06~B*35:01~C*07:02~DRB1*04:07~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0092 | 4 | −0.1447 | 0.7261 | −0.7 |
A*24:14~B*40:02~C*03:04~DRB1*14:02~DRB3*01:01~DQB1*03:01~DQA1*05:03~DPA1*01:03~DPB1*04:02 | 0.0092 | 4 | 0.3376 | <0.0001 | 3.8 |
A*68:03~B*35:01~C*07:02~DRB1*04:07~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0092 | 4 | −0.1447 | 0.7261 | −0.7 |
A*02:01~B*35:43~C*01:02~DRB1*04:07~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0069 | 3 | 1.0000 | <0.0001 | 3.5 |
A*02:06~B*40:02~C*03:04~DRB1*04:11~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*02:01 | 0.0069 | 3 | 0.7427 | <0.0001 | 3.5 |
A*02:06~B*40:02~C*03:04~DRB1*14:02~DRB3*01:01~DQB1*03:01~DQA1*05:03~DPA1*01:03~DPB1*04:02 | 0.0069 | 3 | 0.1993 | 0.0003 | 3.1 |
A*02:06~B*52:01~C*03:03~DRB1*04:04~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0069 | 3 | 1.0000 | <0.0001 | 3.5 |
A*24:02~B*35:12~C*04:01~DRB1*04:07~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0069 | 3 | −0.2211 | 0.6297 | −0.9 |
A*24:02~B*39:05~C*07:02~DRB1*04:07~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0069 | 3 | 0.1901 | 0.0025 | 2.9 |
A*24:02~B*39:06~C*07:02~DRB1*04:04~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0069 | 3 | 0.4865 | <0.0001 | 3.4 |
A*68:01~B*39:01~C*07:02~DRB1*04:11~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0069 | 3 | 0.7180 | 0.0001 | 3.3 |
A*68:01~B*39:05~C*07:02~DRB1*04:11~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0069 | 3 | 0.0073 | 0.9166 | 0.2 |
A*68:01~B*39:05~C*07:02~DRB1*16:02~DRB5*02:02~DQB1*03:01~DQA1*05:05~DPA1*01:03~DPB1*04:02 | 0.0069 | 3 | 0.0692 | 0.1387 | 2.0 |
A*68:03~B*35:01~C*07:02~DRB1*04:07~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*02:02~DPB1*05:01 | 0.0069 | 3 | 0.7300 | <0.0001 | 3.4 |
A*02:01~B*18:01~C*07:01~DRB1*11:04~DRB3*02:02~DQB1*03:01~DQA1*05:05~DPA1*02:02~DPB1*05:01 | 0.0046 | 2 | 1.0000 | <0.0001 | 2.8 |
A*02:01~B*35:12~C*04:01~DRB1*04:11~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.0599 | 0.5566 | 0.9 |
A*02:01~B*35:12~C*04:01~DRB1*08:02~NULL~DQB1*04:02~DQA1*04:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.1206 | 0.0719 | 2.1 |
A*02:06~B*35:01~C*07:02~DRB1*04:07~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.0137 | 0.8113 | 0.4 |
A*02:06~B*39:08~C*07:02~DRB1*04:07~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.6135 | 0.0076 | 2.6 |
A*02:06~B*40:02~C*03:04~DRB1*04:11~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*02:01 | 0.0046 | 2 | 0.4854 | <0.0001 | 2.8 |
A*02:06~B*40:02~C*03:04~DRB1*04:11~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.0455 | 0.6421 | 0.8 |
A*24:02~B*35:12~C*04:01~DRB1*04:11~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | −0.3709 | 0.4685 | −1.5 |
A*24:02~B*39:05~C*07:02~DRB1*04:07~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.0189 | 0.8626 | 0.3 |
A*24:02~B*39:05~C*07:02~DRB1*08:02~NULL~DQB1*04:02~DQA1*04:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.1071 | 0.0959 | 2.0 |
A*24:02~B*40:02~C*03:04~DRB1*14:02~DRB3*01:01~DQB1*03:01~DQA1*05:03~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.4795 | <0.0001 | 2.7 |
A*24:14~B*35:01~C*04:01~DRB1*04:04~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.3185 | <0.0001 | 2.7 |
A*24:14~B*35:01~C*04:01~DRB1*04:04~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*02:02~DPB1*05:01 | 0.0046 | 2 | 0.6592 | <0.0001 | 2.8 |
A*24:14~B*40:02~C*03:04~DRB1*04:11~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.0770 | 0.4699 | 1.1 |
A*31:01~B*40:02~C*03:04~DRB1*04:11~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*02:02~DPB1*05:01 | 0.0046 | 2 | 1.0000 | 0.0003 | 2.8 |
A*68:01~B*40:08~C*03:04~DRB1*04:03~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.6450 | <0.0001 | 2.7 |
A*68:01~B*40:08~C*03:04~DRB1*04:03~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.3609 | 0.0015 | 2.6 |
A*68:01~B*40:08~C*03:04~DRB1*04:07~DRB4*01:05~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 1.0000 | <0.0001 | 2.8 |
A*68:02~B*53:01~C*04:01~DRB1*13:03~DRB3*02:02~DQB1*02:02~DQA1*02:01~DPA1*02:02~DPB1*11:01 | 0.0046 | 2 | 1.0000 | <0.0001 | 2.8 |
A*68:03~B*35:01~C*07:02~DRB1*04:11~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | −0.6973 | 0.0380 | −4.3 |
A*68:03~B*35:01~C*07:02~DRB1*16:02~DRB5*02:02~DQB1*03:01~DQA1*05:05~DPA1*01:03~DPB1*02:01 | 0.0046 | 2 | 1.0000 | <0.0001 | 2.8 |
A*68:03~B*39:01~C*07:02~DRB1*04:07~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 1.0000 | 0.0004 | 2.8 |
A*68:03~B*39:05~C*07:02~DRB1*04:07~DRB4*01:03~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.0365 | 0.4454 | 1.2 |
A*68:03~B*39:05~C*07:02~DRB1*08:02~NULL~DQB1*04:02~DQA1*04:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.0326 | 0.4848 | 1.1 |
A*68:03~B*39:05~C*07:02~DRB1*16:02~DRB5*02:02~DQB1*03:01~DQA1*05:05~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.0304 | 0.5242 | 1.0 |
A*68:05~B*39:05~C*07:02~DRB1*04:07~DRB4*01:01~DQB1*03:02~DQA1*03:01~DPA1*01:03~DPB1*04:02 | 0.0046 | 2 | 0.2270 | 0.1611 | 1.8 |
