Table 3 Tryptophan-to-stop codon mutations detected in HIV DNA fragments obtained from the woman and transmitting partner PBMCs by Sanger and next-generation sequencing.
HIV-1 gene | Number (%) of sequences harboring mutations generating tryptophan codon-to-stop codon changes | |
|---|---|---|
Woman PBMCs (Sanger/NGS) | Transmitting partner PBMCs | |
gag | −/2 (50%) | 0 |
pol protease | −/1 (100%) | 0 |
pol reverse transcriptase | 0/2 (50%) | 0 |
pol integrase | 0/4 (67%) | 0 |
vif | 1 (11%)/5 (71%) (1 in common) | 0 |
vpr | 1 (17%)/2 (100%) (1 in common) | 0 |
tat | 0/− | 0 |
vpu | 2 (50%)/0 | 0 |
rev | −/− | 0 |
env gp120 | 6 (86%)/0 | 0 |
env gp41 | −/− | 0 |
nef | −/− | 0 |
