Figure 7 | Scientific Reports

Figure 7

From: Power and pitfalls of computational methods for inferring clone phylogenies and mutation orders from bulk sequencing data

Figure 7

Clone phylogenies inferred by six methods, excluding Cloe for which convergence was a problem, on an MA dataset. True clone phylogeny is given in Fig. 1g. MACHINA produced two solutions (b,c). Inferred clones are annotated, and colors correspond to clones in Fig. 1g. All the methods produced either clone lineage M or lineage C/D, which were found in the M5 tumor (Fig. 1h). The first solution of MACHINA (b) produced clone D, and LICHeE produced clones C and D (e). The other methods, CloneFinder (a), Treeomics (d), PhyloWGS (f), and MixPhy (g) produced clone M.

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