Figure 4
From: Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors
Up-regulation of luciferase signal mediated by a single dose of LPS. Bioluminescence imaging persisted more than 4 months during development in mice which received intravenous administration of the AAV8 NFκB biosensor (n = 7). At day 132 of development all the mice received a single dose of LPS which resulted in a significant up-regulation in luciferase expression in the IV injected mice, p < 0.0001.
