Table 3 Survival analysis of clinicopathologic variables for overall survival (OS) and progression-free survival (PFS) in the adult group.

From: Comparative Clinicopathologic Characteristics and Outcomes of Paediatric and Adult Xp11 Translocation Renal Cell Carcinomas: a Retrospective Multicentre Study in China

Variable

One-year

Five-year

One-year

Five-year

P-value

OS

OS

PFS

PFS

Log-rank test

% (SE)

% (SE)

% (SE)

% (SE)

OS

PFS

Sex

    

0.29

0.17

    Male

89.4 (0.06)

71.3 (0.10)

69.2 (0.09)

58.0 (0.09)

  

    Female

100

78.5 (0.07)

85.5 (0.06)

67.3 (0.08)

  

Symptom

    

*

*

    Symptomless

97.3 (0.03)

78.5 (0.08)

83.9 (0.06)

68.2 (0.08)

  

    Haematuria

90.0 (0.07)

78.5 (0.10)

72.0 (0.10)

59.7 (0.11)

  

Abdominal mass

*

  

    Flank pain

100

51.4 (0.19)

72.7 (0.13)

51.9 (0.16)

  

Laterality

    

0.80

0.78

    Left

93.6 (0.04)

71.8 (0.10)

78.5 (0.07)

67.9 (0.09)

  

    Right

97.3 (0.03)

78.2 (0.07)

78.9 (0.07)

60.2 (0.09)

  

Operation

    

0.78

0.16

    RN

95.6 (0.03)

75.9 (0.07)

74.3 (0.06)

57.5 (0.08)

  

    NSS

95.8 (0.04)

72.6 (0.13)

87.5 (0.07)

75.4 (0.10)

  

pT stage

    

<0.01

<0.01

    T1/T2

100

90.0 (0.05)

92.4 (0.04)

82.4 (0.06)

  

    T3/T4

82.4 (0.09)

34.0 (0.13)

36.7 (0.12)

0

  

Nuclear grade

    

0.64

0.50

    1/2

95.3 (0.03)

75.6 (0.07)

79.7 (0.06)

67.1 (0.07)

  

    3/4

96.0 (0.04)

74.6 (0.10)

77.2 (0.08)

53.6 (0.13)

  

AJCC stage

    

<0.01

<0.01

    I/II

100

91.9 (0.05)

93.7 (0.04)

88.9 (0.05)

  

    III/IV

85.7 (0.08)

38.5 (0.12)

46.6 (0.11)

0

  

Local lymph node metastasis

    

<0.01

<0.01

    LN+

84.2 (0.08)

40.3 (0.13)

40.0 (0.11)

0

  

    LN−

100

89.1 (0.05)

93.9 (0.03)

87.3 (0.05)

  

Vena cava tumour thrombosis

    

<0.01

<0.01

    Positive

88.9 (0.11)

22.2 (0.14)

11.1 (0.11)

0

  

    Negative

96.6 (0.02)

85.1 (0.05)

88.6 (0.04)

72.8 (0.06)

  

Adjuvant therapy

    

<0.01

<0.01

    None

95.7 (0.04)

87.7 (0.09)

95.7 (0.04)

85.2 (0.08)

  

    Immunotherapy

100

90.5 (0.07)

86.4 (0.06)

82.7 (0.07)

  

    Targeted therapy

88.9 (0.07)

43.8 (0.12)

44.4 (0.11)

11.1 (0.07)

  

Tumour boundary

    

0.35

0.02

    Clear

97.6 (0.02)

80.0 (0.08)

88.0 (0.05)

71.1 (0.08)

  

    Unclear

92.6 (0.05)

68.6 (0.09)

65.2 (0.09)

50.5 (0.10)

  
  1. RN, Radical nephrectomy; NSS, Nephron-sparing surgery; AJCC, American Joint Committee On Cancer; LN+, Lymph node positivity; LN−, Lymph node negativity; SE, Standard error; *No data or insufficient data for statistical analysis.