Table 1 List of functional and sub-functional category of peptides along with their response information incorporated in PlantPepDB.
Functional Category | Number of Peptides | Sub-functional Category | Response in Plants/Animal/Others |
|---|---|---|---|
Inhibitory in nature | 280 | Protein translation inhibitor (2), Enzyme inhibitor (256), Protease inhibitor (13), Serine protease inhibitor (1), Tyrosinase and melanin inhibitor (3), Tyrosinase inhibitor (5) | Animal |
Toxic | 407 | Toxin (37), Celiac toxic (201), Cytotoxic (169) | Animal |
Immune system related | 65 | Immunomodulatory (35), Immunoregulator (10), Immunostimulating (1), Immunosuppressive (19) | Animal |
Opioid | 8 | Opioid (6), Opioid agonist (1), Opioid antagonist (1) | Animal |
Therapeutic | 1465 | Antiproliferative (9), Anticancer (156), Vasorelaxant (2), Antihypertensive (500), ACE-inhibitor (427), Hypotensive (5), Pore-forming (1), Antithrombotic (7), Antioxidant (227), Anti-inflammatory (13), Anti-amnestic (4), Anti-analgesic (1), Antinociceptive (3), Anxiolytic (2), Diuretic (2), Uterotonic (1), Anti-HIV (37), HIV-1-reverse-transcriptase inhibition (8), Antihyperglycemic (1), Antidiabetic (1), Hypoglycemic (1), DPP-IV inhibitor (3), Estrogen like activity (18), Phagocytosis stimulatory peptide (2), Bile acid binding inhibitor (1), Protein synthesis inhibitor (2), Cyclooxygenase inhibitor (8), HMG-CoA reductase inhibitor (3), Neurotensin inhibitor (1), Anti-allergen (11), Antimalarial (8) | Animal |
Plant defense response | 43 | Alpha-amylase inhibitor (15), Defensive-proteinase inhibitor (3), Trypsin inhibitor (3), Gene expression activator (5), Gene expression stimulator (1), Antifeedant (7), Defense activator (3), Defense gene activator (6) | Plants |
Microbe killing | 2356 | Antimicrobial (1393), Antiparasitic (15), Antiprotist (4), Antibacterial (323), Antiyeast (4), Antifungal (529), Antibiotic (2), Antiviral (83), Antibiofilm (3) | Others |
Invertebrate killing | 209 | Anthelmintic (35), Anti-barnacle (1), Molluscicidal (6), Nematocide (56), Insecticidal (111) | Animal |
Miscellaneous | 231 | Hemolytic (71), Hypocholesterolemic (2), Hypotriglyceridemic (3), Neuropeptide (92), Allergen (9), Enzymatic degradation (54) | Animal |