Figure 7
From: A novel de novo variant of GABRA1 causes increased sensitivity for GABA in vitro

Area under the curve of wild-type and mutated receptors. Area under the curve was calculated at 30 µM (a) and 1 mM GABA (b) in all four receptor types. Statistically significant differences were determined by two-tailed students t-test, where p < 0.05; ***p < 0.001; ****p < 0.0001. Bars are presented as mean ± SEM.