Figure 4
Clustergram of gene array showing up- and downregulation of genes for tissue remodelling and scarring by Alveofact in comparison to control (saline) or fatty gauze. (a) Gene regulation on day 8. (b) Gene regulation on day 14. Note reduced MMP-3 expression on d8 and reduced β-catenin on both days reflecting measurements for E-cadherin expression (see Fig. 3). Data are presented with a standard red-green-map in which red represents values above the mean, black represents the mean, and green represents values below the mean of a row (gene) across all columns (samples). 0 control, FG fatty gauze, Alv at 0.01 and 0.5 mg/mL.
