Figure 6
From: Slc20a1/Pit1 and Slc20a2/Pit2 are essential for normal skeletal myofiber function and survival
Loss of three alleles of skeletal muscle Pit1 and Pit2 impairs muscle function. Voluntary hourly wheel-running activity on day 6 of a daily wheel-running study of P80 females (A, C) and males (B, D) was reduced in a gene-dose dependent fashion. Means ± SEM, n = 5–36, ***p = 0.0002, **p = 0.002, *p = 0.03 vs. WT.
